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Table 1 Mean ± SD of Glx concentrations (mmol L-1 of brain water) and Glx/tCr ratios

From: Effects of isoflurane, sevoflurane, propofol and alfaxalone on brain metabolism in dogs assessed by proton magnetic resonance spectroscopy (1H MRS)

  Dose 1 Dose 2 Dose 3 Arithmetic mean
Mean ± SD Mean ± SD Mean ± SD Mean ± SD
GLX BG Isoflurane 13.568 ± 1.196 13.017 ± 1.037 13.039 ± 1.703 13.146 ± 1.003
Sevoflurane 12.532 ± 1.369 12.931 ± 1.156 13.226 ± 1.266 12.896 ± 1.005
Propofol 12.388 ± 1.066 12.730 ± 1.191 12.839 ± 1.582 12.760 ± 1.105
Alfaxalone 12.941 ± 1.353 13.133 ± 1.670 13.423 ± 1.756 13.166 ± 1.233
PL Isoflurane 11.831 ± 2.167AB 13.119 ± 1.695A 11.821 ± 1.911B 12.345 ± 1.6741
Sevoflurane 11.189 ± 1.375 10.632 ± 1.301 10.767 ± 0.888 10.863 ± 0.99712
Propofol 10.201 ± 1.818 10.165 ± 1.669 10.481 ± 2.286 10.295 ± 1.7222
Alfaxalone 10.087 ± 2.052 10.766 ± 2.084 10.315 ± 1.418 10.390 ± 1.3532
OL Isoflurane 12.957 ± 1.341 12.263 ± 1.648 13.083 ± 1.845 12.913 ± 1.463
Sevoflurane 12.869 ± 2.277 12.311 ± 1.752 12.700 ± 1.539 12.627 ± 1.694
Propofol 12.043 ± 0.400 12.135 ± 0.809 12.587 ± 1.289 12.223 ± 0.646
Alfaxalone 12.555 ± 1.586 12.320 ± 1.075 12.609 ± 1.055 12.495 ± 1.032
GLX/tCr BG Isoflurane 2.326 ± 0.136 2.118 ± 0.144 2.215 ± 0.416 2.196 ± 0.214
Sevoflurane 2.082 ± 0.221 2.032 ± 0.185 2.117 ± 0.180 2.077 ± 0.127
Propofol 2.082 ± 0.199 2.109 ± 0.153 2.136 ± 0.216 2.119 ± 0.141
Alfaxalone 2.045 ± 0.182 2.082 ± 0.232 2.091 ± 0.290 2.073 ± 0.175
PL Isoflurane 2.177 ± 0.365 2.353 ± 0.352 2.110 ± 0.342 2.224 ± 0.306
Sevoflurane 2.064 ± 0.265 1.908 ± 0.240 1.932 ± 0.178 1.968 ± 0.197
Propofol 1.826 ± 0.385 1.858 ± 0.388 1.931 ± 0.516 1.865 ± 0.396
Alfaxalone 1.857 ± 0.365 2.001 ± 0.451 1.915 ± 0.242 1.924 ± 0.272
OL Isoflurane 1.964 ± 0.302 1.800 ± 0.243 2.028 ± 0.278 1.984 ± 0.287
Sevoflurane 1.914 ± 0.353 1.810 ± 0.300 1.870 ± 0.240 1.864 ± 0.282
Propofol 1.777 ± 0.063 1.838 ± 0.147 1.834 ± 0.156 1.839 ± 0.131
Alfaxalone 1.868 ± 0.280 1.839 ± 0.213 1.922 ± 0.193 1.877 ± 0.220
  1. Mean ± SD for the three different doses and the arithmetic mean of the three doses for isoflurane, sevoflurane, propofol and alfaxalone in basal ganglia (BG), parietal lobe (PL) and occipital lobe (OL). Different alphabetical superscripts differ significantly (p < 0.05) between different doses of each anesthetic and different numerical superscripts differ significantly between arithmetic mean Glx concentrations of each anesthetic. For treatment I and S: Dose 1 time 3; Dose 2 time 1; Dose 3 time 2