Geno type
|
No.
|
Nucleotide mutation position/corresponding amino acid substitutiona
|
---|
−42
|
−22
|
−6 &-5
|
47
|
144
|
214
|
237
|
255
|
262
|
399
|
438
|
453
|
498
|
499
|
519
|
606
|
686
|
765
|
797
|
824
|
833
|
---|
C
|
G
|
GG
|
G
|
C
|
G
|
C
|
G
|
T
|
C
|
G
|
T
|
C
|
T
|
T
|
T
|
C
|
T
|
A
|
C
|
T
|
---|
1
|
65
|
−b
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
Sb
|
G(−2)N
| | | | | | | | | | | | | | | | | | |
2
|
5
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
C
|
T
|
C
|
G
|
–
|
–
|
–
|
C
|
–
|
C
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | | | |
S
|
S
|
S
|
S
| | | |
S
| |
S
| | | |
3
|
4
|
T
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
T
|
C
|
G
|
–
|
–
|
–
|
C
|
–
|
C
|
–
|
–
|
–
|
| |
S
|
S
|
G(− 2)N
| | | | | | |
S
|
S
|
S
| | | |
S
| |
S
| | | |
4
|
4
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
T
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | | | | | | | |
S
| | | | | | | | |
5
|
3
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
A
|
| | |
S
|
G(−2)N
| | | | | | | | | | | | | | | |
S278Y
|
6
|
2
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
A
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | | |
S
| | | | | | | | | | | | | |
7
|
2
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
T
|
| | |
S
|
G(−2)N
| | | | | | | | | | | | | | | |
S278F
|
8
|
2
|
–
|
A
|
AA
|
–
|
T
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
C
|
–
|
C
|
C
|
T
|
–
|
| | |
S
|
G(−2)N
| |
S
| | | | | | | | | | |
S
| |
S S T275I
|
9
|
1
|
–
|
A
|
AA
|
–
|
–
|
A
|
–
|
A
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| |
Q72S
|
S
| | | | | | | | | | | | | |
10
|
1
|
–
|
A
|
AA
|
T
|
–
|
–
|
–
|
–
|
–
|
T
|
C
|
G
|
–
|
–
|
–
|
C
|
–
|
C
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
|
S16I
| | | |
S
|
S
|
S
| | | |
S
| |
S
| | | |
11
|
1
|
–
|
A
|
AA
|
–
|
–
|
–
|
A
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | |
S
| | | | | | | | | | | | | | |
12
|
1
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
G
|
–
|
–
|
–
|
A
|
| | |
S
|
G(−2)N
| | | | | | | | | | | | |
A229G
|
S278Y
|
13
|
1
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
A
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | | | | | | | | |
N173 K
| | | | | |
14
|
1
|
–
|
A
|
AA
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
Db
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
| | |
S
|
G(−2)N
| | | | | | | | | |
W167Gc
| | | | | |
- aNucleotide/peptide positions were designated relative to the first nucleotide/amino acid of the mature 훂-hemolysin (S. aureus WOOD46)
- bS synonymous mutation, D deletion mutation, − = no mutation;
- cThe deletion at nucleotide position 499 of Genotype 14 resulted in peptide termination at residue position 169