Skip to main content

Table 4 Nucleotide mutations and corresponding amino acid substitutions of Staphylococcus aureus from cases of clinical mastitis

From: Virulence gene profiles: alpha-hemolysin and clonal diversity in Staphylococcus aureus isolates from bovine clinical mastitis in China

Geno type No. Nucleotide mutation position/corresponding amino acid substitutiona
−42 −22 −6 &-5 47 144 214 237 255 262 399 438 453 498 499 519 606 686 765 797 824 833
C G GG G C G C G T C G T C T T T C T A C T
1 65 b A AA
    Sb G(−2)N                   
2 5 A AA C T C G C C
    S G(−2)N       S S S S     S   S    
3 4 T A AA T C G C C
   S S G(− 2)N        S S S     S   S    
4 4 A AA T
    S G(−2)N           S         
5 3 A AA A
    S G(−2)N                 S278Y
6 2 A AA A
    S G(−2)N      S              
7 2 A AA T
    S G(−2)N                 S278F
8 2 A AA T C C C T
    S G(−2)N   S            S   S S T275I
9 1 A AA A A
    S G(−2)N   Q72S S              
10 1 A AA T T C G C C
    S G(−2)N S16I     S S S     S   S    
11 1 A AA A
    S G(−2)N     S               
12 1 A AA G A
    S G(−2)N              A229G S278Y
13 1 A AA A
    S G(−2)N            N173 K      
14 1 A AA Db
    S G(−2)N           W167Gc      
  1. aNucleotide/peptide positions were designated relative to the first nucleotide/amino acid of the mature 훂-hemolysin (S. aureus WOOD46)
  2. bS synonymous mutation, D deletion mutation, − = no mutation;
  3. cThe deletion at nucleotide position 499 of Genotype 14 resulted in peptide termination at residue position 169