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Table 1 ROTEM and standard coagulation profiles results, before and 24 h after hydroxyethyl starch 130/0.4 infusion

From: Thromboelastometric assessment of hemostasis following hydroxyethyl starch (130/0.4) administration as a constant rate infusion in hypoalbuminemic dogs

  GROUP 1 (1 ml / kg / h) N = 11 GROUP 2 (2 ml / kg / h) N = 9 Institutional reference ranges
ROTEM T0 T1 T0 T1  
In-TEM®
 CT (s) 180 (132–268) 166 (61–209) 188 (112–279) 141 (108–240) 126–363 s
 CFT (s) 63 (45–132) 59 (41–113) 73 (41–86) 58 * (38–81) 47–224 s
 MCF (mm) 72 (56–80) 72 (58–88) 68 (62–77) 72 (62–78) 50–75 mm
 α angle (°) 77 (65–81) 79 (69–82) 76 (73–82) 78 * (74–82) 55–81 °
Ex-TEM®
 CT (s) 44 (27–61) 45 (20–77) 46 (30–89) 40 (33–80) 29–92 s
 CFT (s) 67 (38–159) 78 (49–132) 81 (51–96) 62 (49–92) 54–275 s
 MCF (mm) 77 (60–82) 70 (64–83) 70 (66–81) 72 * (67–86) 36–73 mm
 α angle (°) 76 (61–83) 76 (65–82) 74 (71–80) 77 * (73–81) 47–79 °
Fib-TEM®
 CT (s) 47 (31–107) 39 (21–57) 45 (29–92) 39 (32–80) 14–102 s
 MCF (mm) 25 (7–38) 16 (8–46) 15 (9–30) 20 (14–78) 6–26 mm
 α angle (°) 77,5 (70–86) 76 (30–86) 76,5 (67–81) 77 (71–84) 40–78 °
 MCEplatelet 294 (142–404) 211 (169–441) 206 (175–383) 235 (183–571) 50–235
Standard coagulation
 aPTT (s) 12.5 (9.6–15.4) 12.3 (8.7–16) 13.9 (12.1–16) 14.5 (11.7–16) 12–16 s
 PT (s) 7.5 (6.6–9.6) 7.15 (6.6–9.9) 7.4 (6.2–10) 7.3 (6.3–10) 8–10 s
 Fibrinogen (g/L) 3.5 (2.5–8.5) 3.6 (2.4–7.9) 3.4 (2.2–7.4) 4.1 (2.2–7.1) 1.5–4.50 (g/L)
  1. Values are expressed as median (minimum-maximum)
  2. Values of institutional reference ranges for ROTEM parameters are expressed as 95% confidence intervals14
  3. In-TEM® intrinsic thromboelastometry pathway, Ex-TEM® extrinsic thromboelastometry pathway, Fib-TEM® functional fibrinogen, CT clotting time, CFT clot formation time, MCF maximum clot firmness, PT prothrombin time, aPTT activated partial thromboplastin time
  4. * Indicates statistically significant differences between T0 and T1 (P < 0.05)