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Table 1 Physiochemical characteristics of the feline leucine-rich glioma-inactivated (LGI) proteins

From: Molecular cloning and characterization of the family of feline leucine-rich glioma-inactivated (LGI) genes, and mutational analysis in familial spontaneous epileptic cats

Physiochemical characteristics LGI1 LGI2 LGI3 LGI4
Amino acid 557 549 548 538
Total number of atoms 8959 8728 8683 8323
Molecular weight (Da) 63,817.99 62,249.12 61,887.77 58,979.10
Isoelectric point 8.39 6.21 8.46 7.60
Asp + Glu 56 63 51 49
Arg + Lys 61 58 56 50
Extinction coefficients 84520a/83770b 80955a/80330b 91050a/90300b 71805a/70930b
Aliphatic index 85.75 88.23 88.47 97.25
Instability index 42.89 53.34 44.27 47.50
Grand average of hydropathicity −0.227 −0.119 −0.143 0.064
  1. aComputed value based on the assumption that all cysteine residues appear as half cysteine’s; bAssuming that no cysteine appears as a half cysteine