From: Trypsin-independent porcine epidemic diarrhea virus US strain with altered virus entry mechanism
Group | Inoculum | Age at inoculation (numbers) | No. of death (fatality %) | Clinical symptoms | Virus shedding |
---|---|---|---|---|---|
1 | PEDV KD P120 | 2-day old (N = 5) | 3/5 (60%) | Diarrhea: 3–9 DPI | Started at 2 DPI |
2 | PEDV AA P103 | 2-day-old (N = 14) | 7/14 (50%) | Diarrhea: 2–9 DPI | Started at 1 DPI |
3 | PEDV 8aa P40 | 2 or 4-day old (N = 24) | 20/24 (83.3%) | Diarrhea: 3–8 DPI | Started at 2 DPI |
4 | PEDV 8aa P70 | 1-day-old (N = 15) | 1/15 (6.7%) 1 died (non-PEDV related) | Loose stool at 1–2 DPI | Limited virus shedding |
5 | PEDV 8aa P105 | 1- or 2-day old (N = 16) | 0/16 (0%) | No diarrhea | Limited virus shedding |