Table 2 Reference genes for canine OS and their cellular function(s)
Gene symbol | Name | Function |
|---|---|---|
RPS5 | Ribosomal protein S5 | Ribosomal protein that is a component of the 40S subunit, belongs to the S7P family of ribosomal proteins |
RPS19 | Ribosomal protein S19 | Ribosomal protein that is a component of the 40S subunit, belongs to the S19E family of ribosomal proteins |
HPRT | Hypoxanthine guanine phosphoribosyl transferase | Purine metabolism, salvage of purines from degraded RNA |
HNRNPH | Heterogeneous nuclear ribonucleoprotein H | RNA-binding protein that forms a complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport |
RPL8 | Ribosomal protein L8 | Ribosomal protein that is a component of the 60S subunit which catalyzes protein synthesis |
GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme in glycolysis and gluconeogenesis pathway |
B2M | β-2-Microglobulin | Beta chain of MHC class I molecules |
SRPR | Signal recognition particle receptor | Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system |
GUSB | β-glucuronidase | Role in degradation of dermatan and keratin sulphates |