Table 2 Pathways previously implicated in the equine exercise response that were significantly enriched among predicted targets of the differntially expressed miRNAs
KEGG pathway | P value | n genes | n miRNAs |
|---|---|---|---|
B cell receptor signalling pathway | 1.4637E-06 | 16 | 4 |
Ubiquitin mediated proteolysis | 1.4637E-06 | 25 | 4 |
Neurotrophin signalling pathway | 3.75787E-06 | 22 | 4 |
T cell receptor signalling pathway | 3.75787E-06 | 20 | 4 |
TGF-beta signalling pathway | 9.00943E-06 | 15 | 4 |
PI3K-Akt signalling pathway | 4.61509E-05 | 43 | 4 |
Long-term potentiation | 0.000171436 | 13 | 4 |
Regulation of actin cytoskeleton | 0.000171436 | 28 | 4 |
MAPK signalling pathway | 0.000293552 | 34 | 4 |
Jak-STAT signalling pathway | 0.000485158 | 22 | 4 |
Axon guidance | 0.000671812 | 22 | 3 |
Arrhythmogenic right ventricular cardiomyopathy | 0.000834821 | 13 | 3 |
Hepatitis B | 0.000838527 | 21 | 4 |
Transcriptional misregulation in cancer | 0.002038503 | 26 | 4 |
Hypertrophic cardiomyopathy | 0.002113538 | 13 | 3 |
Insulin signalling pathway | 0.002113538 | 19 | 4 |
Mucin type O-Glycan biosynthesis | 0.002113538 | 6 | 3 |
Prostate cancer | 0.0021797 | 13 | 4 |
mTOR signalling pathway | 0.002349162 | 11 | 4 |
Acute myeloid leukaemia | 0.003086604 | 9 | 4 |
Adherens junction | 0.004193219 | 14 | 4 |