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Table 8 Predicted inhibition percentage of COX-1 and COX-2 for the observed robenacoxib concentrations at 1 and 5 h; mean (SD) [max], N = 80

From: Safety evaluation of the interchangeable use of robenacoxib (Onsior™) tablets and solution for injection in dogs

 

Time

Group 2

Group 3

Group 4

% inhibition COX-1

1

24

(9)

[50]

23

(10)

[44]

29

(11)

[53]

% inhibition COX-1

5

6

(5)

[22]

10

(8)

[30]

11

(10)

[36]

% inhibition COX-2

1

82

(23)

[99]

79

(27)

[98]

87

(20)

[99]

% inhibition COX-2

5

24

(27)

[88]

39

(32)

[95]

41

(32)

[97]