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Table 1 Background data and initial MIC values of the isolated Mycoplasma synoviae strains

From: Antibiotic susceptibility profiles of Mycoplasma synoviae strains originating from Central and Eastern Europe

Strain data MIC values (μg/ml)
Strain ID Hosta Production phase Farm Region Country Year EFX DIF CTC DX OTC TYL TIL TVN N SPC LCM LCM-SPC TIA VAL FFC
MYCAV 31 ch layer 1 Nógrád Hungary 2014 0.625 5 0.5 0.078 1 ≤0.25 ≤0.25 ≤0.25 32 1 1 2 (0.666/1.334) ≤0.039 ≤0.039 2
MYCAV 79 t broiler 2 Győr-Moson-Sopron Hungary 2014 0.312 1.25 ≤0.25 0.078 0.5 ≤0.25 ≤0.25 ≤0.25 32 1 1 2 (0.666/1.334) 0.078 ≤0.039 2
MYCAV 102 t broiler 3 Vas Hungary 2014 1.25 1.25 0.5 0.078 0.5 ≤0.25 ≤0.25 ≤0.25 32 1 1 1 (0.333/0.667) 0.078 ≤0.039 2
MYCAV 119 t broiler 4 Komárom-Esztergom Hungary 2014 0.312 1.25 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 1 2 (0.666/1.334) 0.078 ≤0.039 2
MYCAV 130 t broiler 5 Győr-Moson-Sopron Hungary 2014 10 5 0.5 0.078 0.5 ≤0.25 ≤0.25 ≤0.25 32 2 1 2 (0.666/1.334) 0.156 ≤0.039 4
MYCAV 167 ch breeder 6 Jász-Nagykun-Szolnok Hungary 2015 0.625 0.625 0.5 ≤0.039 ≤0.25 ≤0.25 ≤0.25 ≤0.25 8 1 ≤0.25 0.5 (0.167/0.333) ≤0.039 ≤0.039 2
MYCAV 168 ch layer 7 Pardubice Czech Republic 2015 >10 5 2 0.312 1 ≤0.25 0.5 ≤0.25 8 2 1 1 (0.333/0.667) 0.156 ≤0.039 8
MYCAV 170 ch breeder 8 Győr-Moson-Sopron Hungary 2015 2.5 2.5 0.5 0.078 0.5 ≤0.25 ≤0.25 ≤0.25 16 2 0.5 0.5 (0.167/0.333) 0.156 ≤0.039 8
MYCAV 173 ch layer 9 Oryol Russia 2015 10 2.5 1 0.156 0.5 ≤0.25 1 ≤0.25 4 1 0.5 0.5 (0.167/0.333) ≤0.039 ≤0.039 2
MYCAV 174 ch layer 10 Oryol Russia 2015 >10 10 4 0.312 1 ≤0.25 4 ≤0.25 32 2 1 2 (0.666/1.334) 0.078 ≤0.039 8
MYCAV 183 ch broiler 11 Komárom-Esztergom Hungary 2015 1.25 1.25 0.5 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 >64 8 0.5 1 (0.333/0.667) 0.078 ≤0.039 8
MYCAV 185 ch breeder 12 Szabolcs-Szatmár-Bereg Hungary 2015 >10 5 0.5 0.312 0.5 2 64 0.5 16 2 >64 2 (0.666/1.334) 0.156 ≤0.039 8
MYCAV 186 ch layer 13 Borsod-Abaúj-Zemplén Hungary 2015 >10 2.5 2 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 64 2 0.5 0.5 (0.167/0.333) 0.312 ≤0.039 2
MYCAV 188 ch breeder 14 Zala Hungary 2015 >10 10 4 0.312 1 ≤0.25 ≤0.25 ≤0.25 32 2 0.5 1 (0.333/0.667) ≤0.039 ≤0.039 2
MYCAV 189 ch layer 15 Cherkasy Ukraine 2015 10 5 8 0.312 1 ≤0.25 2 ≤0.25 32 2 1 1 (0.333/0.667) 0.078 ≤0.039 8
MYCAV 190 ch layer 16 Cherkasy Ukraine 2015 >10 10 4 0.312 0.5 ≤0.25 2 ≤0.25 32 2 1 0.5 (0.167/0.333) 0.078 ≤0.039 8
MYCAV 194b ch breeder 17 unknown Slovenia 2002 0.625 1.25 ≤0.25 ≤0.039 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 4 0.5 0.5 (0.167/0.333) 0.156 ≤0.039 4
MYCAV 197c ch breeder 18 unknown Slovenia 2002 0.625 10 0.5 ≤0.039 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 ≤0.25 0.5 2 (0.666/1.334) 0.078 ≤0.039 4
MYCAV 198d ch unknown 19 unknown Slovenia 2008 0.625 5 ≤0.25 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 16 4 0.5 1 (0.333/0.667) 0.312 ≤0.039 8
MYCAV 217 t broiler 20 Békés Hungary 2015 2.5 10 1 0.078 ≤0.25 ≤0.25 0.5 ≤0.25 64 1 1 1 (0.333/0.667) 0.625 ≤0.039 8
MYCAV 236 ch breeder 21 Veszprém Hungary 2015 0.312 1.25 1 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 16 1 0.5 0.5 (0.167/0.333) 0.078 ≤0.039 0.5
MYCAV 249 ch layer 22 South Moravia Czech Republic 2016 5 10 ≤0.25 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 >64 4 1 1 (0.333/0.667) 0.078 ≤0.039 4
MYCAV 256 ch layer 23 South Moravia Czech Republic 2016 10 5 1 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 >64 4 1 2 (0.666/1.334) 0.156 ≤0.039 4
MYCAV 257 ch layer 24 Fejér Hungary 2016 >10 10 2 0.156 1 ≤0.25 ≤0.25 ≤0.25 32 2 1 1 (0.333/0.667) 0.156 ≤0.039 4
MYCAV 259 ch breeder 25 unknown Serbia 2016 >10 5 0.5 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 ≤0.25 0.5 (0.167/0.333) 0.312 ≤0.039 2
MYCAV 261 t broiler 26 Komárom-Esztergom Hungary 2016 1.25 1.25 0.5 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 16 2 ≤0.25 0.5 (0.167/0.333) ≤0.039 ≤0.039 4
MYCAV 262 t broiler 27 Komárom-Esztergom Hungary 2016 0.625 1.25 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 16 1 0.5 1 (0.333/0.667) ≤0.039 ≤0.039 8
MYCAV 263 t broiler 28 Győr-Moson-Sopron Hungary 2016 1.25 1.25 0.5 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 8 1 ≤0.25 0.5 (0.167/0.333) ≤0.039 ≤0.039 2
MYCAV 268 t broiler 29 Tolna Hungary 2016 1.25 2.5 0.5 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 64 2 0.5 1 (0.333/0.667) 0.156 ≤0.039 8
MYCAV 272 ch layer 30 Ternopil Ukraine 2016 0.625 1.25 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 >64 4 2 1 (0.333/0.667) 0.625 ≤0.039 4
MYCAV 274 ch broiler 31 Vas Hungary 2016 2.5 2.5 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 64 4 1 2 (0.666/1.334) 0.312 ≤0.039 8
MYCAV 277 t broiler 32 Veszprém Hungary 2016 1.25 1.25 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 0.5 1 (0.333/0.667) 0.078 ≤0.039 4
MYCAV 278 t broiler 33 Veszprém Hungary 2016 1.25 1.25 ≤0.25 0.156 ≤0.25 ≤0.25 ≤0.25 ≤0.25 16 2 0.5 1 (0.333/0.667) ≤0.039 ≤0.039 2
MYCAV 281 t broiler 34 Somogy Hungary 2016 0.312 0.625 ≤0.25 0.156 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 1 1 (0.333/0.667) 0.156 ≤0.039 8
MYCAV 282 ch layer 13 Borsod-Abaúj-Zemplén Hungary 2016 10 5 0.5 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 >64 4 1 2 (0.666/1.334) ≤0.039 ≤0.039 0.5
MYCAV 284 t broiler 35 Burgenland Austria 2016 1.25 2.5 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 0.5 1 (0.333/0.667) 0.156 ≤0.039 4
MYCAV 285 t broiler 36 Burgenland Austria 2016 1.25 2.5 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 32 2 ≤0.25 0.5 (0.167/0.333) 0.078 ≤0.039 4
MYCAV 288 t broiler 37 Burgenland Austria 2016 1.25 2.5 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 >64 1 0.5 1 (0.333/0.667) 0.078 ≤0.039 4
MYCAV 291 t broiler 38 Győr-Moson-Sopron Hungary 2016 0.625 2.5 0.5 0.156 0.5 ≤0.25 ≤0.25 ≤0.25 32 1 ≤0.25 0.5 (0.167/0.333) 0.078 ≤0.039 4
MYCAV 300 ch breeder 14 Zala Hungary 2016 >10 10 1 0.312 1 ≤0.25 1 ≤0.25 64 2 1 1 (0.333/0.667) 0.078 ≤0.039 4
MYCAV 306 t broiler 4 Komárom-Esztergom Hungary 2016 1.25 2.5 ≤0.25 0.078 ≤0.25 ≤0.25 ≤0.25 ≤0.25 16 1 1 1 (0.333/0.667) 0.078 ≤0.039 4
  1. Abbreviations of antibiotics: EFX enrofloxacin, DIF difloxacin, DX doxycycline, OTC oxytetracycline, CTC chlortetracycline, TYL tylosin, TIL tilmicosin, TVN tylvalosin, N neomycin, SPC spectinomycin, LCM lincomycin, TIA tiamulin, VAL valnemulin, FFC florfenicol
  2. aAll strains were isolated from the trachea of the animals, abbreviations stand for: ch chicken, t turkey
  3. bMYCAV194 is sub-clone of strain ULB02/T6 [41]
  4. cMYCAV197 is sub-clone of strain IT2/A [41]
  5. dMYCAV198 is sub-clone of strain ULB08/T3 [42]