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Table 1 Percentage (%) of positive samples to IFNγ assay (95% Wilson’s confidence intervals) from M. bovis-infected deer

From: Development and evaluation of an interferon gamma assay for the diagnosis of tuberculosis in red deer experimentally infected with Mycobacterium bovis

  15 dpi 30 dpi 60 dpi
  < 0.1 (%) < 0.05 (%) < 0.1 (%) < 0.05 (%) < 0.1 (%) < 0.05 (%)
bPPD 92.8 (68.5–98.7) 92.8 (68.5–98.7) 100 (79.6–100) 100 (79.6–100) 75 (40.9–92.9) 75 (40.9–92.9)
P22 85.7 (60.1–96) 92.8 (68.5–98.7) 100 (79.6–100) 100 (79.6–100) 75 (40.9–92.9) 87.5 (52.9–97.8)
ESAT-6/CFP-10 92.3 (66.7–98.6) 92.3 (66.7–98.6) 85.7 (60.1–96) 100 (79.6–100) 75 (40.9–92.9) 75 (40.9–92.9)
Rv3615c 40 (19.8–64.3) 40 (19.8–64.3) 26.6 (10.9–52) 26.6 (10.9–52) 25 (7.1–59.1) 37.5 (13.7–69.4)
Rv3020c 53.3 (41.7–84.8) 66.6 (30.1–75.2) 73.3 (48–89.1) 100 (79.6–100) 75 (40.9–92.9) 87.5 (52.9–97.8)
ESAT-6/CFP-10 + Rv3615c 92.3 (66.7–98.6) 92.3 (66.7–98.6) 86.6 (62.1–96.3) 100 (79.6–100) 75 (40.9–92.9) 87.5 (52.9–97.8)
ESAT-6/CFP-10 + Rv3020c 93.3 (70.2–98.8) 93.3 (70.2–98.8) 100 (79.6–100) 100 (79.6–100) 75 (40.9–92.9) 87.5 (52.9–97.8)
  1. IFNγ interferon gamma, bPPD bovine purified protein derivative, ESAT-6/CFP-10 early secretory antigenic target-6 kDa and culture filtrate protein 10; dpi: days post-infection