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Table 1 Percentage (%) of positive samples to IFNγ assay (95% Wilson’s confidence intervals) from M. bovis-infected deer

From: Development and evaluation of an interferon gamma assay for the diagnosis of tuberculosis in red deer experimentally infected with Mycobacterium bovis

 

15 dpi

30 dpi

60 dpi

 

< 0.1 (%)

< 0.05 (%)

< 0.1 (%)

< 0.05 (%)

< 0.1 (%)

< 0.05 (%)

bPPD

92.8 (68.5–98.7)

92.8 (68.5–98.7)

100 (79.6–100)

100 (79.6–100)

75 (40.9–92.9)

75 (40.9–92.9)

P22

85.7 (60.1–96)

92.8 (68.5–98.7)

100 (79.6–100)

100 (79.6–100)

75 (40.9–92.9)

87.5 (52.9–97.8)

ESAT-6/CFP-10

92.3 (66.7–98.6)

92.3 (66.7–98.6)

85.7 (60.1–96)

100 (79.6–100)

75 (40.9–92.9)

75 (40.9–92.9)

Rv3615c

40 (19.8–64.3)

40 (19.8–64.3)

26.6 (10.9–52)

26.6 (10.9–52)

25 (7.1–59.1)

37.5 (13.7–69.4)

Rv3020c

53.3 (41.7–84.8)

66.6 (30.1–75.2)

73.3 (48–89.1)

100 (79.6–100)

75 (40.9–92.9)

87.5 (52.9–97.8)

ESAT-6/CFP-10 + Rv3615c

92.3 (66.7–98.6)

92.3 (66.7–98.6)

86.6 (62.1–96.3)

100 (79.6–100)

75 (40.9–92.9)

87.5 (52.9–97.8)

ESAT-6/CFP-10 + Rv3020c

93.3 (70.2–98.8)

93.3 (70.2–98.8)

100 (79.6–100)

100 (79.6–100)

75 (40.9–92.9)

87.5 (52.9–97.8)

  1. IFNγ interferon gamma, bPPD bovine purified protein derivative, ESAT-6/CFP-10 early secretory antigenic target-6 kDa and culture filtrate protein 10; dpi: days post-infection