Fig. 6From: Avian infectious bronchitis virus disrupts the melanoma differentiation associated gene 5 (MDA5) signaling pathway by cleavage of the adaptor protein MAVSIBV cleaves MAVS at an early stage of infection. CEK cells were infected with IBV at an MOI of 1. At the indicated times post-infection, cells were lysed and the expression of MAVS proteins were analyzed by Western blot using an anti-MAVS antibody (top panel). The IBV-encoded N protein was detected with an anti-N antibody (second panel). β-actin was detected as a loading control (bottom panel)Back to article page