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Table 1 Treatment groups

From: Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro

Group

Treatment

1

Control

2

Mepivacaine only

3

Mepivacaine + morphine

4

Mepivacaine + MgSO4

5

Mepivacaine + morphine + MgSO4

6

Morphine only

7

MgSO4 only

8

Morphine + MgSO4

9

Bupivacaine only

10

Bupivacaine + morphine

11

Bupivacaine + MgSO4

12

Bupivacaine + morphine + MgSO4

  1. Treatment groups to which synoviocyte-articular cartilage explant co-cultures were exposed. Concentrations used were mepivacaine 4.4 mg/ml, bupivacaine 2.2 mg/ml, morphine 2.85 mg/ml and magnesium sulphate 37 mg/ml diluted in DMEM complete to a total volume of 2 ml per well