Effect of gastric acid-suppressive therapy and biological variation of serum gastrin concentrations in dogs with chronic enteropathies

Table 1 Summary of the serum gastrin concentrations and characteristics of the study population

Patient characteristics	Serum gastrin (in ng/L) in acid-suppressant-naïve dogs	P	Serum gastrin (in ng/L) in acid-suppressant-treated dogs	P
Age
< 6 years	9.9 [9.9–14.9]	0.0770	10.6 [9.9–43.9]	0.5496
> 6 years	10.8 [9.9–22.8]	0.0770	18.0 [9.9–34.4]	0.5496
Sex
Female	9.9 [9.9–15.3]	0.5102	11.2 [9.9–31.8]	0.4276
Male	10.0 [9.9–19.4]	0.5102	13.5 [9.9–44.6]	0.4276
Breed
Purebred	10.1 [9.9–19.4]	0.1744	11.4 [9.9–35.0]	0.7206
Mixed breed	9.9 [9.9–14.4]	0.1744	15.8 [9.9–46.9]	0.7206
German Shepherd (GSD)	12.1 [9.9–15.1]	0.8011	N/A	N/A
Non-GSD	9.9 [9.9–20.0]	0.8011	11.4 [9.9–35.0]	N/A
Yorkshire Terrier (YT)	11.3 [9.9–14.8]	0.6147	9.9 [9.9–9.9]	0.1202
Non-YT	10.1 [9.9–19.5]	0.6147	13.5 [9.9–36.3]	0.1202
Clinical disease severity (CCECAI score)
Mild to moderate	9.9 [9.9–14.8]	*0.0363*	11.2 [9.9–39.8]	0.9911
Severe to very severe	12.8 [9.9–25.0]	*0.0363*	17.6 [9.9–31.2]	0.9911
Clinical signs
Vomiting	9.9 [9.9–18.0]	0.6869	10.8 [9.9–33.1]	0.1354
No vomiting	9.9 [9.9–17.3]	0.6869	22.8 [10.3–48.2]	0.1354
Diarrhea	10.0 [9.9–17.5]	0.5810	24.5 [9.9–12.4]	*0.0090*
No diarrhea	9.9 [9.9–16.3]	0.5810	24.5 [9.9–50.0]	*0.0090*
Weight loss	9.9 [9.9–19.3]	0.6704	19.2 [9.9–44.7]	0.2113
No weight loss	10.3 [9.9–15.1]	0.6704	10.7 [9.9–27.1]	0.2113
Hypo−/anorexia	10.4 [9.9–23.0]	0.5200	15.2 [9.9–31.8]	0.4983
No hypo−/anorexia	9.9 [9.9–16.1]	0.5200	11.4 [9.9–47.5]	0.4983

ISSN: 1746-6148