TY - JOUR AU - Caol, Sanjie AU - Divers, Thomas AU - Crisman, Mark AU - Chang, Yung-Fu PY - 2017 DA - 2017/09/29 TI - In vitro susceptibility of Borrelia burgdorferi isolates to three antibiotics commonly used for treating equine Lyme disease JO - BMC Veterinary Research SP - 293 VL - 13 IS - 1 AB - Lyme disease in humans is predominantly treated with tetracycline, macrolides or beta lactam antibiotics that have low minimum inhibitory concentrations (MIC) against Borrelia burgdorferi. Horses with Lyme disease may require long-term treatment making frequent intravenous or intramuscular treatment difficult and when administered orally those drugs may have either a high incidence of side effects or have poor bioavailability. The aim of the present study was to determine the in vitro susceptibility of three B. burgdorferi isolates to three antibiotics of different classes that are commonly used in practice for treating Borrelia infections in horses. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-017-1212-3 DO - 10.1186/s12917-017-1212-3 ID - Caol2017 ER -