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Table 2 Immunological parameters measured in the BALF at D39 and D53

From: Efficacy of one dose vaccination against experimental infection with two Mycoplasma hyopneumoniae strains

Parameter

Experimental groups

   
 

NCG (# = 5)

PCG (# = 20)

VG (# = 20)

P-value

Ig G ± SD (OD-values)

 D39

0 ± 0 a

0.069 ± 0.14 a

0.31 ± 0.65 a

0.366

 D53

0.38 ± 0.17 a

2.25 ± 0.91 b

2.41 ± 0.88 b

0.005

Ig A ± SD (OD-values)

 D39

0 ± 0 a

0.067 ± 0.18 a

0.55 ± 0.99 a

0.359

 D53

0.18 ± 0.14 a

2.10 ± 0.75 b

2.08 ± 0.58 b

0.005

TNF-α ± SD (pg/ml)

 D39

23.61 ± 1.74 a

18.56 ± 4.40 a

21.12 ± 4.56a

0.029

 D53

16.03 ± 1.10 a

14.53 ± 5.95 a

15.15 ± 2.40a

0.065

IL-1 ± SD (pg/ml)

 D39

32.47 ± 1.77 a

239.63 ± 511.35 a

247.13 ± 606.71a

0.367

 D53

17.61 ± 1.98 a

1283.39 ± 1075.65 b

53.04 ± 54.23 a

<0.001

IL-6 ± SD (pg/ml)

 D39

130.33 ± 18.65 ab

242.24 ± 122.23 a

164.64 ± 84.48 b

0.03

 D53

148.10 ± 8.89 a

493.35 ± 494.70 b

259.80 ± 333.38 a

0.004

  1. D39: two weeks after challenge
  2. D53: necropsy
  3. a,bDifferent superscripts in one row are statistically different (P < 0.05)
  4. NCG negative control group, PCG positive control group, VG vaccination group, SD standard deviation, D Day of the study, OD optical densities, # number