Grading of inflammation | |||
---|---|---|---|
Severity | Duration | ||
Mild | ≤400 inflammatory cells in one high power field (400X magnification) | Acute | Predominance of polymorphonuclear leukocytes (neutrophils and eosinophils), accompanied by prominent inflammatory edema. |
Moderate | 400–900 inflammatory cells in one high power field (400X magnification) | Subacute | Polymophonuclear inflammatory infiltrate mixed with mononuclear cells (lymphocytes, macrophages and plasma cells). Edema present, but mild. |
Severe | >900 inflammatory cells in one high power field (400X magnification) | Chronic | Large numbers of plasma cells, lymphocytes, macrophages and significantly fewer polymorphonuclear leukocytes, accompanied by small blood vessel proliferation and fibroblasts (granulation tissue). |
 |  | Chronic - active | Large numbers of plasma cells, lymphocytes, macrophages and polymorphonuclear leukocytes, accompanied by proliferation of small blood vessels and fibroblasts (granulation tissue). |