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Table 5 Mean and 95% posterior credible intervals (PCI) for the sensitivity (Se) and specificity (Sp) of serial and parallel testing using one serum ELISA and the fecal PCR

From: Estimation of the sensitivity and specificity of two serum ELISAs and one fecal qPCR for diagnosis of paratuberculosis in sub-clinically infected young-adult French sheep using latent class Bayesian modeling

 

Mean (95% PCI)

ELISA A – Fecal qPCR

ELISA B – Fecal qPCR

Serial testing

Seser

8.7 (3.8; 15.8)

8.5 (3.5; 16.0)

 

Spser

99.8 (99.3 – 100.0)

99.3 (98.5; 99.9)

Parallel testing

Separ

56.6 (38.8;76.1)

55.8 (37.4; 75.9)

 

Sppar

93.8 (91.8; 95.6)

93.1 (90.7; 95.1)

  1. Estimates were obtained with model 1, with doubtful ELISA results and fecal qPCR Ct ≤ 42 treated as positive
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BMC Veterinary Research

ISSN: 1746-6148

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