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Table 5 Mean and 95% posterior credible intervals (PCI) for the sensitivity (Se) and specificity (Sp) of serial and parallel testing using one serum ELISA and the fecal PCR

From: Estimation of the sensitivity and specificity of two serum ELISAs and one fecal qPCR for diagnosis of paratuberculosis in sub-clinically infected young-adult French sheep using latent class Bayesian modeling

  Mean (95% PCI)
ELISA A – Fecal qPCR ELISA B – Fecal qPCR
Serial testing Seser 8.7 (3.8; 15.8) 8.5 (3.5; 16.0)
  Spser 99.8 (99.3 – 100.0) 99.3 (98.5; 99.9)
Parallel testing Separ 56.6 (38.8;76.1) 55.8 (37.4; 75.9)
  Sppar 93.8 (91.8; 95.6) 93.1 (90.7; 95.1)
  1. Estimates were obtained with model 1, with doubtful ELISA results and fecal qPCR Ct ≤ 42 treated as positive