Estimation of the sensitivity and specificity of two serum ELISAs and one fecal qPCR for diagnosis of paratuberculosis in sub-clinically infected young-adult French sheep using latent class Bayesian modeling

Table 2 Bayesian Deviance Information Criterion (DIC) for model 1 to 3 under different scenarios

		Deviance Information Criterion
Doubtful ELISA results	Fecal qPCR positive cut-off	Model 1^a	Model 2^b	Model 3^c
Positive	Ct ≤ 42	120.4	134.2	227.9
Positive	Ct ≤ 40	114.3	130.1	197.5
Negative	Ct ≤ 42	115.6	128.2	222.1
Negative	Ct ≤ 40	114.3	127.5	194.5

^aModels with pairwise dependence between ELISA A and ELISA B for sensitivity and pairwise dependence between the three tests for specificity
^bModels with pairwise dependence between ELISA A and ELISA B for sensitivity and specificity and assuming conditional independence of fecal qPCR
^cModels assuming fully conditional independence between the three tests

ISSN: 1746-6148