|  | Target Attainment Rate | |||
---|---|---|---|---|---|
 |  | P.multocida | A.pleuropneumoniae | ||
Dose duration | Level of bacterial kill | 50% | 90% | 50% | 90% |
0-24Â h | Bacteriostatic | 0.12 | 0.29 | 0.03 | 0.07 |
Bactericidal | 0.27 | 0.64 | 0.05 | 0.12 | |
4 log10 reduction | 0.43 | 1.01 | 0.06 | 0.14 | |
0-48Â h | Bacteriostatic | 0.19 | 0.44 | 0.16 | 0.39 |
Bactericidal | 0.40 | 0.95 | 0.28 | 0.66 | |
4 log10 reduction | 0.64 | 1.51 | 0.34 | 0.82 | |
0-72Â h | Bacteriostatic | 0.26 | 0.60 | 0.22 | 0.53 |
Bactericidal | 0.56 | 1.31 | 0.38 | 0.92 | |
4 log10 reduction | 0.88 | 2.08 | 0.47 | 1.14 |