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Table 3 Population used in final analysis, dose of imepitoin, AWG and PANAS at specific time points and owner satisfaction

From: The use of imepitoin (Pexion™) on fear and anxiety related problems in dogs – a case series

Case No.

Baseline

Week 1

Week 11

Decision

Max. dose of imepitoin (mg/kg BID)

Score Reduction Negative Activation (Baseline to Decision)

% Score Reduction Negative Activation (Baseline to Decision)

Owner Satisfaction

Continuation of treatment at owner’s expense – Y/N (C/T) = basis of use

AWG

Dose (mg/kg)

AWG

Dose (mg/kg)

AWG

Dose (mg/kg)

AWG

Dose (mg/kg)

2

46.70

0

26.50

8.6

9.00

30.2

4.00

30.2

30.2

−0.05

−6.25

S

Y (C)

3

11.57

0

2.50

9.4

0.50

19.8

2.50

19.8

19.8

−0.17

−22.67

S

Y (T)

5

32.33

0

24.50

10.8

11.00

21.6

0.00

21.6

21.6

−0.38

−47.50

VS

Y (C)

6

3.36

0

0.88

11.8

0.00

3.9

0.00

11.8

11.8

−0.04

−4.76

VS

Y (T)

7

20.94

0

4.36

10.5

5.00

10.5

5.00

10.5

10.5

−0.36

−46.15

VS

Y (C)

8

19.75

0

3.33

11.7

0.59

11.7

0.00

23.5

23.5

−0.04

−6.25

S

Y (T)

9

12.00

0

7.33

9.9

3.34

9.9

6.00

19.8

19.8

−0.18

−30.14

S

Y (C or T)

10

23.67

0

27.50

9.7

6.67

19.3

6.50

19.3

19.3

−0.16

−22.22

VS

Y (T)

11

28.07

0

13.38

12.7

9.00

19.0

9.67

19.0

19.0

−0.15

−21.13

S

Y (T)

12

34.75

0

34.00

10.7

9.64

19.2

17.58

29.9

29.9

−0.07

−8.54

PP

Y (C)

13

29.75

0

3.50

9.9

16.67

19.8

2.50

29.7

29.7

−0.31

−34.07

S

Y (C or T)

14

28.58

0

12.78

10.0

11.75

20.0

5.50

20.0

20.0

−0.15

−17.24

PP

N

15

34.91

0

21.00

13.6

8.00

30.5

1.00

30.5

30.5

−0.07

−8.54

VD

N

16

7.61

0

4.59

10.8

7.00

29.8

7.00

29.8

29.8

0.05

9.80

PP

N

17

28.00

0

21.00

10.0

1.00

5.0

1.00

5.0

10.0

−0.03

−5.88

VS

Y (C)

19

28.89

0

19.84

9.7

16.33

9.7

15.50

19.4

19.4

−0.16

−18.18

VS

Y (C or T)

20

6.33

0

3.33

10.9

8.00

21.8

9.50

21.8

21.8

−0.22

−30.14

PP

N

  1. AWG Average weekly global score, Baseline Baseline week, Decision Decision point (11–19 weeks); Y yes, N no, VS very satisfied, S satisfied, PP partly satisfied/partly dissatisfied, D dissatisfied, VD very dissatisfied, C continuous use, T tactical use