Safety pharmacology and subchronic toxicity of jinqing granules in rats

BMC Veterinary Research

Table 8 Effect of subchronic administration of Jinqing granules on the organ coefficient (g/ g*100%) of male and female rats (n = 20)

Parameters	gender	Heart	Liver	Spleen	Lung	Kidney	Testis or Ovary
Control group	Male	0.35 ± 0.01	3.24 ± .024	0.30 ± 0.04	0.51 ± 0.05	0.79 ± 0.06	1.25 ± 0.12
Control group	Female	0.37 ± 0.05	3.26 ± 0.19	0.31 ± 0.03	0.47 ± 0.02	0.76 ± 0.06	0.05 ± 0.01
saline group	Male	0.37 ± 0.03	3.36 ± 0.10	0.28 ± 0.04	0.53 ± 0.05	0.80 ± 0.04	1.27 ± 0.10
saline group	Female	0.39 ± 0.03	3.45 ± 0.14	0.29 ± 0.03	0.52 ± 0.02	0.77 ± 0.05	0.04 ± 0.01
2 g/kg	Male	0.35 ± 0.02	3.37 ± 0.19	0.32 ± 0.05	0.54 ± 0.06	0.78 ± 0.04	1.24 ± 0.14
2 g/kg	Female	0.37 ± 0.04	3.37 ± 0.36	0.27 ± 0.06	0.55 ± 0.08	0.81 ± 0.11	0.05 ± 0.01
4 g/kg	Male	0.35 ± 0.01	3.39 ± 0.24	0.31 ± 0.05	0.52 ± 0.04	0.75 ± 0.06	1.21 ± 0.10
4 g/kg	Female	0.36 ± 0.02	3.27 ± 0.22	0.31 ± 0.07	0.50 ± 0.05	0.79 ± 0.04	0.05 ± 0.01
8 g/kg	Male	0.36 ± 0.04	3.44 ± 0.24	0.28 ± 0.04	0.54 ± 0.05	0.78 ± 0.06	1.28 ± 0.11
8 g/kg	Female	0.35 ± 0.02	3.32 ± 0.18	0.30 ± 0.03	0.52 ± 0.05	0.76 ± 0.02	0.05 ± 0.01
16 g/kg	Male	0.34 ± 0.05	3.49 ± 0.37^*	0.26 ± 0.05	0.54 ± 0.13	0.83 ± 0.11	1.41 ± 0.13^*
16 g/kg	Female	0.36 ± 0.03	3.52 ± 0.16^*	0.26 ± 0.05	0.54 ± 0.04	0.80 ± 0.06	0.06 ± 0.01

ISSN: 1746-6148