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Table 7 Effect of subchronic administration of Jinqing granules on serum biochemistry measurements in rats (n = 20)

From: Safety pharmacology and subchronic toxicity of jinqing granules in rats

Parameters

ALT(U/L)

AST(U/L)

TP(g/L)

TG(g/L)

GLU(mmol/L)

UREA(mmol/L)

CREA (mmol/L)

T-Bil(g/L)

ALB(g/L)

Control group

32.17 ± 5.59

105.58 ± 31.84

57.59 ± 4.12

0.34 ± 0.17

5.33 ± 1.77

5.64 ± 1.18

32.76 ± 3.95

2.32 ± 0.43

25.81 ± 4.46

Saline group

34.13 ± 3.90

111.45 ± 22.26

55.33 ± 5.57

0.43 ± 0.15

5.15 ± 2.67

5.51 ± 1.36

33.94 ± 6.81

2.36 ± 0.33

26.38 ± 4.14

2 g/kg

31.63 ± 3.84

119.03 ± 31.76

56.16 ± 3.64

0.32 ± 0.08

5.46 ± 1.77

5.66 ± 0.88

29.55 ± 8.76

2.87 ± 0.27

26.76 ± 4.67

4 g/kg

35.72 ± 5.99

119.78 ± 15.37

59.07 ± 5.52

0.33 ± 0.21

5.19 ± 1.64

5.46 ± 0.96

31.74 ± 7.14

2.44 ± 0.41

27.29 ± 5.33

8 g/kg

33.96 ± 3.97

125.76 ± 20.33

55.98 ± 3.73

0.34 ± 0.07

5.04 ± 1.44

6.02 ± 0.66

35.28 ± 6.94

3.15 ± 0.35

25.91 ± 4.58

16 g/kg

37.69 ± 3.03

137.63 ± 26.44*

58.45 ± 4.09

0.45 ± 0.09

4.88 ± 2.31

6.23 ± 1.07

36.66 ± 5.46

3.43 ± 0.42*

27.61 ± 8.61

  1. Values represent means ± SD
  2. ALT alanine aminotransferase, AST aspartate aminotransferase, TP total protein, TG triglycerides, GLU glucose, UREA blood urea nitrogen, CREA creatinine, TC total cholesterol, ALB albumin
  3. *P < 0.05, significantly difference from control values