Fig. 1From: Small-sized newborn dogs skeletal development: radiologic, morphometric, and histological findings obtained from spontaneously dead animalsRepresentative histological images of an OCT-0 (a), an OCT-1 (b), an OCT-2 (c) and an OCT-3 (d). According with the progression of age, the enlargement of the lacunae (a, b, c, head arrow) and the thickening and calcification of the extra cellular matrix (a, b, c, arrows) indicate the appearance of an ossification centre. In OCT-2, primary trabeculae delimit lacunae containing bone marrows cells (c, d, asterisk). In OCT-3, neoformed bone tissue appears, laying on the trabeculae (d, arrow). a, b, c stained with haematoxylin-eosin; D stained with a Masson’s Trichrome stain. Bar 0.01 mmBack to article page