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Table 2 Clinical parameters (estimated means and ranges) before and after intra-articular injection of 3 μg E. coli O55:B5 lipopolysaccharide

From: Changes in concentrations of haemostatic and inflammatory biomarkers in synovial fluid after intra-articular injection of lipopolysaccharide in horses

 

Pain score (Fig. 1b)

Heart rate (Fig. 1c)

Respiratory rate (Fig. 1d)

Rectal temperature (Fig. 1e)

Carpus circumference (Fig. 1f)

Carpus skin temperature (Fig. 1g)

  

Beats/min

Breaths/min

°C

Centimetres

°C

Hours relative to LPS injection

Estimated mean

Range

Estimated mean

Range

Estimated mean

Range

Estimated mean

Range

Estimated mean

Range

Estimated mean

Range

−120

0.02

0–2

38.4

32–48

12.8

8–20

37.7

37.2–38.1

33.9

30.3–36.8

26.6

23.84–29.68

−96

0.02

0–1.5

38.0

32–40

14.8

12–20

37.5

37.2–38.0

33.7

30.6–36.5

28.5

24.62–32.70

−24

0.01

0–3

39.3

36–48

12.2

8–16

37.6

37.3–38.2

33.8

32.9–36.5

28.8

22.84–31.60

0

0.04

0–3

37.6

36–40

13.9

10–28

37.6

37.2–38.0

33.8

30.4–36.4

29.1

26.34–31.60

2

5.50**

1–13

46.1

40–54

21.3

12–56

37.6

36.9–38.4

34.1

30.6–36.7

31.9*

24.80–30.92

4

10.80***

7–14

47.9*

40–52

32.8*

14–68

37.9

37.0–38.5

34.4*

30.6–37.5

32.1*

25.36–33.66

8

6.82**

3–11

46.5

40–56

17.9

12–28

38.5**

38.1–39.1

34.4

30.4–37.5

32.2**

29.68–34.28

16

3.60*

1–7

43.0

32–52

16.0

12–28

38.3*

38.0–38.7

34.9***

31.2–38.2

32.7***

26.50–35.30

24

0.88

0–8

38.4

28–44

12.2

9–20

37.6

37.2–37.9

34.9***

31.3–38.6

33.5***

32.30–34.68

36

0.03

0–1.5

36.6

32–40

10.5

8–12

37.6

37.1–37.9

35.0***

31.0–38.5

32.3**

29.64–33.88

48

0

0–1

36.2

28–40

11.9

9–20

37.7

37.3–38.1

34.9***

31.0–38.5

32.6**

30.42–34.02

72

0

0–1

35.2

32–40

11.2

8–16

37.5

36.9–38.0

34.9***

31.4–38.0

32.1**

30.92–33.96

144

0

0–1

36.6

32–40

11.8

9–36

37.4

37.1–37.8

34.6***

30.8–38.0

30.2

28.64–32.08

  1. Asterisks designate significant difference from post-injection hour −120 (* = P < 0.05; ** = P < 0.01 and *** = P < 0.001)
  2. LPS lipopolysaccharide