Fig. 1

Clinical parameters recorded in 6 horses before and after intra-articular injection of 3 μg E. coli O55:B5 lipopolysaccharide (LPS) in one antebrachiocarpal joint (a) Association of American Equine Practitioners [AAEP] lameness scale; b composite measure pain score; c heart rate; d respiratory rate; e rectal temperature; f circumference of injected carpus in centimetres [cm]; g skin temperature over injected carpus). Individual horse responses and estimated means ± standard error of the mean (black line) are depicted. Results of the statistical analyses are shown in Table 2