Table 1 Pathways and number of genes up- or down-regulated in CoPS-1/2, CoPS-3/4, and CoNS-3/4 bovine groups

Complement and coagulation cascades

22

21

18

Cytokine-cytokine receptor interaction

31

19

22

Chemokine signaling pathway

25

25

18

Antigen processing and presentation

13

19

18

NOD-like receptor signaling pathway

11

15

10

Cell adhesion molecules (CAMs)

16

24

14

Leukocyte trans-endothelial migration

16

22

12

Toll-like receptor signaling pathway

13

14

11

Gap junction

12

–

–

T cell receptor signaling pathway

–

17

–

Natural killer cell mediated cytotoxicity

–

15

–

Immune network for IgA production

12

12

10

Cytosolic DNA-sensing pathway

–

8

–