Impact of growth matrix on pharmacodynamics of antimicrobial drugs for pig pneumonia pathogens

BMC Veterinary Research

Table 4 Chemical composition of broths^a and pig and calf sera: mean and standard deviation (SD) (n = 3 batches)^a

Matrix	Total protein (g/L)	Albumin (g/L)	Globulin (g/L)	Sodium (mmol/L)	Potassium (mmol/L)	Calcium (mmol/L)	Magnesium (mmol/L)	Chloride (mmol/L)	Inorganic phosphorus (mmol/L)	Urea (mmol/L)	Creatinine (μmol/L)	Glucose (mmol/L)	Iron (μmol/L)	Unsaturated Iron Binding Capacity (μmol/L)
Porcine serum	79.3	40.3	39.0	153	7.13	2.59	0.98	115	2.82	4.67	139	5.47	19.1	78.00
SD	2.20	0.17	2.03	4.4	0.06	0.14	0.09	8.96	0.61	3.35	5.5	0.84	0.15	0.36
Bovine serum	74.3	38.1	37.1	148	7.07	2.55	1.00	108	3.28	5.23	149	4.43	22.2	71.00
SD	3.65	2.11	1.31	15.4	1.04	0.55	0.17	7.55	0.98	0.60	9.9	0.29	0.61	0.43
MHB	3.23	0.00	3.23	125	2.49	0.13	0.23	99.23	2.55	0.93	61.3	2.57	9.47	-6.90
SD	0.12	0.00	0.12	0.2	0.01	0.02	0.00	0.32	0.03	0.06	2.31	0.06	0.15	0.44
CAMHB	4.10	0.07	4.03	127	2.87	5.21	4.20	117	2.96	2.97	83.3	2.57	9.53	-7.20
SD	0.44	0.06	0.46	11.5	0.21	2.14	1.68	5.29	0.34	0.64	2.08	0.25	0.17	1.24
CB	12.6	0.10	12.5	130	14.58	0.22	1.41	112	4.99	2.90	217	12.90	63.9	-56.50
SD	0.20	0.00	0.20	0.1	0.01	0.01	0.02	0.26	0.02	0.10	2.31	0.00	0.62	1.74
BHI	9.67	0.10	9.57	168	10.01	0.13	0.25	123	6.86	5.97	418	10.20	7.50	-3.17
SD	0.21	0.00	0.21	0.2	0.01	0.01	0.01	0.56	0.07	0.06	3.61	0.20	0.10	1.11
TSB	9.07	0.10	9.00	118	9.56	0.05	0.18	79.33	4.85	2.17	260	11.77	6.86	-2.20
SD	0.06	0.06	0.10	0.1	0.01	0.02	0.00	0.06	0.02	0.06	1.53	0.15	0.25	1.74
VFM	11.4	0.87	10.5	132	38.73	0.33	1.16	104	14.31	4.87	198	3.40	25.9	-3.00
SD	0.26	0.12	0.15	3.5	0.31	0.03	0.10	4.04	0.44	0.72	9.07	0.10	0.52	1.31

^aMueller Hinton Broth (MHB), Cation Adjusted Mueller Hinton Broth (CAMHB),, Veterinary Fastidious Medium (VFM), Columbia Broth supplemented with NAD (CB), Brain Heart Infusion broth (BHIB), Tryptic Soy broth (TSB) and Veterinary Fastidious Medium (VFM)

ISSN: 1746-6148