Fig. 3

The histology of red-eared slider turtle skin. Sections taken from the lateral and bed margins of the wound in insulin-treated (a) and control (b) turtles at 2 DPW. There is a noticeable palisade of acidophilic plasma, fibrin (arrows) and heterophils exudate. At higher magnification, note that infiltrating macrophages (arrows) are more prominent in insulin-treated wound bed edges (c) that in control wounds (d). At 7 DPW re-epithelisation of the lateral edges is observed in both groups (e and f), but insulin-treated wounds show a better differentiated epidermal strata and BMZ (e and f; blue arrows) as well as higher number of fibroblasts (e, black arrows) than control wounds (f, black arrows) in the granulation tissue