Table 4 Summary of results
From: The effects of different velogenic NDV infections on the chicken bursa of Fabricius
| Â | Infection of NDV AF2240 | Infection of NDV IBS002 |
|---|---|---|
Cell population changes | • Increment of T lymphocytes and macrophages, depletion of B lymphocytes compared to uninfected control. • Higher increment of macrophages and depletion of B lymphocytes compared of IBS002 infection. | • Increment of T lymphocytes and macrophages, depletion of B lymphocytes compared to uninfected control. • Lower increment of macrophages and depletion of B lymphocytes compared of AF2240 infection. |
Oxidative stress | • Increment of NO and MDA content compared to uninfected control. • Higher increment of NO and MDA content compared to IBS002 infection. | • Increment of NO and MDA content compared to uninfected control. • Lower increment of NO and MDA content compared to AF2240 infection. |
Expression of pro-inflammatory and anti-inflammatory cykotines/chemokine (CXCLi1, IFNɣ, IL18 and IL10) | • Increment of pro-inflammatory cytokines/chemokines (CXCLi2, IFNɣ, IL18) compared to uninfected control. • Anti-inflammatory IL10 was detected in the bursa at day 3 and 4 post infection but not at day 1 and uninfected control. • Higher increment of pro-inflammatory cytokines/chemokines (CXCLi2, IFNɣ, IL18) compared to IBS002 infection. | • Increment of pro-inflammatory cytokines/chemokines (CXCLi2, IFNɣ, IL18) compared to uninfected control. • Higher anti-inflammatory IL10 was observed in day 3 and day 4 bursa compared to AF2240 infection. • Lower increment of pro-inflammatory cytokines/chemokines (CXCLi2, IFNɣ, IL18) compared to AF2240 infection. |
Viral load | • Viral load was detected in in the bursa at day 3 and 4 post infection but not at day 1 and uninfected control. • Lower detected viral load compared to IBS002 infection. | • Viral load was detected in in the bursa at day 3 and 4 post infection but not at day 1 and uninfected control. • Higher detected viral load compared to AF2240 infection. |
Apoptosis of IgM+ cells | • Increment of IgM+ apoptotic population over the infection time. • Higher increment of IgM+ cell apoptosis compared to IBS002 infection. | • Increment of IgM+ apoptotic population over the infection time. • Lower increment of IgM+ cell apoptosis compared to AF2240 infection. |