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Table 1 Precision of CRP determination in pooled serum samples with CRP concentrations below a clinical decision limit (A1 - A2) as well as pooled serum samples with clinically relevant CRP concentrations

From: Evaluation of a species-specific C-reactive protein assay for the dog on the ABX Pentra 400 clinical chemistry analyzer

 

Intra-assay CV

Inter-assay CV

Between run CV

Between day CV

Level

Mean

CRP concentration

(mg/l)

SD (mg/l)

CV%

SD (mg/l)

CV%

SD (mg/l)

CV%

A1

2.3

0.72

31.1

n.d.

n.d.

n.d.

n.d.

A2

3.8

0.35

9.3

n.d.

n.d.

n.d.

n.d.

A

7.2

0.87

12.1

0.56

7.8

0.44

6.1

B

58.4

1.08

1.9

1.25

2.1

2.7

4.6

C

103.9

0.88

0.9

0.91

0.9

1.9

1.8

D

272.1

1.85

0.7

4.98

1.8

2.8

1.1

  1. A1, A2: CVs for intra-assay imprecision of two canine serum pools analyzed 20 times in a single run without recalibration.
  2. A – D: Inter- and intra-assay CVs of 6 canine serum pools analyzed in duplicates twice daily over 5 days.
  3. CVs not fulfilling the quality specifications i.e., are higher than 12.2% [32] are marked in bold letters.Abbreviations: n.d. = not done, SD = standard deviation; CV = coefficient of variation.