Fig. 7

Acute phase response to implant surgery in three female harbor seal pups. Fibrinogen and haptoglobin concentrations (upper panel), as well as globulin and albumin concentrations (lower panel) from surgery at approximately 6 weeks of age through release 11 weeks after surgery. Samples were collected at surgery, and at weeks 1, 2, 3, 4, 5, 7, 9 and 11. No fibrinogen assays were conducted on surgery days. Pre-surgery values were averaged from available samples collected approximately 4 weeks before surgery (lower panel only). Data points are averages from available samples, and vertical lines connect highest and lowest sample at each week. Reference values for female harbor seal pups under three months of age (whisker boxes on left side of each panel, from n = 42 animals), and over three months of age (whisker boxes on right side of each panel, from n = 21 animals) were calculated from available data as described under methods (lower panel only)