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Table 1 Study design and number of dogs that received each procedure

From: Clinical, serological and echocardiographic examination of healthy field dogs before and after vaccination with a commercial tetravalent leptospirosis vaccine

Time point

T0

T1

T2

T3

Days after first presentation

0

20–28

41–54

368–434

Procedure/number of dogs

    

 Vaccination

48

48

-

44

 Clinical examination

48

48

48

44

 Echocardiography

24

24

-

-

 MAT

48

-

48

44

 Haematology

48

-

48

-

 Blood biochemistry

36

-

36

-

 cTroponin I

29

-

29

-

Number of dogs receiving other vaccine components

    

 Nobivac® DHPPi

16

3

-

-

 Nobivac® Pi

10

1

-

-