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Table 2 Estimates of the diagnostic specificity (Sp) and sensitivity (Se) of the field IMS-LFD and laboratory-based IMS-qPCR and IMS-culture tests for M. bovis in faeces from 100 live captured badgers and 30 live captive badgers relative to live diagnostic test results, obtained using McNemar’s test (95% confidence intervals are indicated in parentheses)

From: Development of a novel immunochromatographic lateral flow assay specific for Mycobacterium bovis cells and its application in combination with immunomagnetic separation to test badger faeces

Test result

Putative TB infected

Putative Non-infected

Total

Diagnostic sensitivity, Se

Diagnostic specificity, Sp

IMS-LFD +

5

5

10

0.081

0.926

IMS-LFD -

57

63

120

(0.027–0.178)

(0.837–0.976)

 

62

68

130

  

IMS-qPCR +

36

20

56

0.581

0.706

IMS-qPCR -

26

48

74

(0.449–0.705)

(0.583–0.811)

 

62

68

130

  

IMS-culture +

27

14

41

0.436

0.794

IMS-culture -

35

54

89

(0.310–0.567)

(0.678–0.882)

 

62

68

130

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