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Table 1 Criteria used for distribution of affected dogs into subgroups

From: Relation of antioxidant status at admission and disease severity and outcome in dogs naturally infected with Babesia canis canis

Uncomplicated babesiosis N = 29

Complicated babesiosis dogs that developed at least one of listed complication N = 11

Dogs without any listed complication

Complication

Criteria

Renal dysfunction

Creatinine >180 μmol/L

Respiratory system dysfunction

Dyspnoea with typical nasal discharge or radiographic evidence of pulmonary oedema

Hepatic dysfunction

ALT >176 U/L, AP >360 U/L, and Bilirubin* >100 μmol/L

Muscular involvement

CPK > 600 U/L

Central nervous system dysfunction

a modified Glasgow coma scale <9**

Additional complication***

Secondary infection

WBC > 17 × 109/L (neutropenia with lymphopenia)

Pancreatitis

Positive SNAP cPL test

  1. cPL canine pancreas-specific lipase
  2. *We included a total bilirubin serum concentration greater than 100 μmol/L as an additional criterion for hepatic dysfunction [62]
  3. **Modified Glasgow coma scale: Welzl et al. [12]
  4. ***Pancreatitis [13] as well as signs of secondary infection were not considered as main complication, they were only mentioned (since being detected) as an additional complication