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Table 7 Relative expression profiles of immune-related genes in PBMC of FCoV-positive cats

From: Expression profiles of immune mediators in feline Coronavirus-infected cells and clinical samples of feline Coronavirus-positive cats

Cat status

Cat ID

CCL8 (MCP2)

CXCL10 (IP10)

MX1

Viperin (RSAD2)

Negative

1*

ND

ND

ND

1 ± 0bc

Non-effusive

2

ND

18.67 ± 0.33b

6.79 ± 1.8e

−1.88 ± 0.27bc

3

16.32 ± 5.48c

ND

0.91 ± 0.1cd

ND

6

ND

ND

0.03 ± 0a

−86.21 ± 0.01a

14

0.42 ± 0.02a

ND

1.45 ± 0.36d

−28.01 ± 0.02b

15

ND

ND

0.58 ± 0.04c

−94.34 ± 0.01a

16

ND

ND

0.32 ± 0.07b

−39.84 ± 0.02b

Effusive

4

ND

ND

0.05 ± 0a

ND

7

0.1 ± 0.05a

0.23 ± 0.22a

13.62 ± 5.07fg

4.87 ± 1.39cd

8

ND

ND

3773.07 ± 67.71j

437.28 ± 31.23f

9

ND

ND

7309.7 ± 52.55k

50.48 ± 3.44e

5

1.08 ± 0.38b

19.17 ± 0c

19.14 ± 0.02gh

4.95 ± 0.31cd

10

ND

ND

56.48 ± 13.47i

7.91 ± 5.25de

11

ND

ND

6.79 ± 0.74ef

−3.35 ± 0.17c

12

ND

ND

16.37 ± 5.13g

1.83 ± 0.45bcd

13

ND

ND

26.9 ± 1.61h

10.16 ± 1.08de

  1. ND Not detected
  2. *Average expression of three healthy cats as negative controls. Relative expression (ΔΔCq) was calculated by normalizing to the reference gene (GAPDH) and negative controls
  3. Note: Data are presented as means ± SEM of three replicates. Different alphabets indicate significant difference following Duncan post hoc comparison of each column (p < 0.05)