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Table 3 Relative expression of immune-related genes following FIPV 79–1146 infection of CRFK cells

From: Expression profiles of immune mediators in feline Coronavirus-infected cells and clinical samples of feline Coronavirus-positive cats

Time points (hpi)

CCL8 (MCP2)

CXCL10 (IP10)

CCL17

MX1

Viperin (RSAD2)

0

1 ± 0a

1 ± 0a

1 ± 0a

1 ± 0a

1 ± 0c

3

21.67 ± 0.57d

13,341.2 ± 197.75c

39.68 ± 1.61e

4.49 ± 0.62c

−13.04 ± 0a

12

3.41 ± 0.07b

8712.95 ± 343.29b

3.56 ± 0b

9.16 ± 1.27d

−7.82 ± 0.02b

24

4.92 ± 0.04c

1,835,241.44 ± 7662.16d

22.87 ± 0.69d

2.69 ± 0.11b

5.72 ± 0.03d

48

40,322.18 ± 14.38f

8,569,241.92 ± 44,483.37e

39.86 ± 0.6e

900.72 ± 4.25f

353.53 ± 1.82e

72

21,651.02 ± 510.17e

8,776,535.79 ± 30,986.02e

8.51 ± 0.44c

517.06 ± 5.38e

583.3 ± 9.86f

  1. Note: Data are presented as means ± SEM of three replicates from two independent experiments. Different alphabets above the data indicate significant difference following Duncan post hoc comparison of each column (p < 0.05). Relative expression (ΔΔCq) was calculated by normalizing with the reference gene (GAPDH) and the negative controls