TY - JOUR AU - Zapata, Rizaldy C. AU - Meachem, Melissa D. AU - Cardoso, Natalia Cavalca AU - Mehain, Susan O. AU - McMillan, Chantal J. AU - Snead, Elisabeth R. AU - Chelikani, Prasanth K. PY - 2017 DA - 2017/04/04 TI - Differential circulating concentrations of adipokines, glucagon and adropin in a clinical population of lean, overweight and diabetic cats JO - BMC Veterinary Research SP - 85 VL - 13 IS - 1 AB - Dyslipidemia, dysregulated adipokine secretion and alteration in glucagon and adropin concentrations are important obesity-related factors in the pathophysiology of human Type 2 diabetes; however, their roles in the pathophysiology of feline diabetes mellitus are relatively unknown. Here, we determined the concentrations of circulating leptin, adiponectin, pro-inflammatory cytokines, glucagon, adropin, triglycerides, and cholesterol, in non-diabetic lean and overweight cats and newly diagnosed diabetic cats. Client-owned cats were recruited and assigned into 3 study groups: lean, overweight and diabetic. Fasting blood samples were analyzed in lean, overweight and diabetic cats at baseline and 4 weeks after consumption of high protein/low carbohydrate standardized diet. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-017-1011-x DO - 10.1186/s12917-017-1011-x ID - Zapata2017 ER -