Time (hr) | Inoculated with PBS | Inoculated with P.multocida B:2 | Inoculated with LPS extracted from P.multocida B:2 | Inoculated with OMPs extracted from P.multocida B:2 | |||
---|---|---|---|---|---|---|---|
Control –G1 | Oral route –G2 | Subcutaneous route - G3 | Oral route- G4 | Intravenous route – G5 | Oral route- G 6 | Subcutaneous route - G7 | |
0 | 0.32 ± 0.01a | 0.31 ± 0.00a | 0.33 ± 0.01a | 0.32 ± 0.01a | 0.33 ± 0.01a | 0.32 ± 0.00a | 0.32 ± 0.00a |
2 | 0.32 ± 0.01ab | 0.30 ± 0.00bc | 0.27 ± 0.01c | 0.32 ± 0.00ab | 0.33 ± 0.00a | 0.30 ± 0.00abc | 0.31 ± 0.01abc |
4 | 0.31 ± 0.00ab | 0.29 ± 0.00bcd | 0.25 ± 0.02d | 0.31 ± 0.00a | 0.31 ± 0.01abc | 0.29 ± 0.00abc | 0.28 ± 0.01cd |
6 | 0.30 ± 0.00a | 0.28 ± 0.01a | 0.24 ± 0.01a | 0.30 ± 0.00a | 0.29 ± 0.02a | 0.29 ± 0.01a | 0.27 ± 0.01a |
8 | 0.33 ± 0.00a | 0.28 ± 0.01b | 0.23 ± 0.00b | 0.29 ± 0.00ab | 0.28 ± 0.01ab | 0.28 ± 0.01ab | 0.25 ± 0.02b |
10 | 0.32 ± 0.00a | 0.26 ± 0.01b | 0.21 ± 0.01b | 0.29 ± 0.01ab | 0.27 ± 0.01b | 0.27 ± 0.01b | 0.24 ± 0.02b |
12 | 0.33 ± 0.00a | 0.26 ± 0.00bc | 0.19 ± 0.00d | 0.28 ± 0.01b | 0.25 ± 0.01bc | 0.26 ± 0.01bc | 0.23 ± 0.00c |
24 | 0.31 ± 0.00a | 0.25 ± 0.02b | 0.27 ± 0.01b | 0.25 ± 0.01b | 0.25 ± 0.01b | 0.21 ± 0.01b | |
36 | 0.32 ± 0.0la | 0.24 ± 0.01b | 0.27 ± 0.02b | 0.24 ± 0.00b | 0.23 ± 0.02b | 0.20 ± 0.0b | |
48 | 0.31 ± 0.0la | 0.24 ± 0.01bc | 0.26 ± 0.00b | 0.23 ± 0.01bc | 0.23 ± 0.01bc | 0.20 ± 0.00c | |
60 | 0.31 ± 0.00a | 0.23 ± 0.00b | 0.24 ± 0.00b | 0.22 ± 0.02b | 0.21 ± 0.02b | 0.19 ± 0.01b | |
72 | 0.33 ± 0.00a | 0.23 ± 0.01b | 0.22 ± 0.01b | 0.22 ± 0.00b | 0.21 ± 0.01b | 0.18 ± 0.01b | |
120 | 0.32 ± 0.00a | 0.21 ± 0.00b | 0.22 ± 0.02b | 0.21 ± 0.01a | 0.2 ± 0.00a | ||
168 | 0.32 ± 0.00a | 0.19 ± 0.00b | 0.22 ± 0.00b | 0.20 ± 0.00b | 0.20 ± 0.01b | ||
216 | 0.31 ± 0.00a | 0.18 ± 0.01b | 0.19 ± 0.01b | 0.20 ± 0.01b | 0.19 ± 0.02b | ||
264 | 0.33 ± 0.00a | 0.18 ± 0.01b | 0.21 ± 0.01b | 0.18 ± 0.02b | 0.18 ± 0.02b | ||
312 | 0.32 ± 0.00a | 0.17 ± 0.01b | 0.21 ± 0.01b | 0.18 ± 0.01b | 0.19 ± 0.01b | ||
360 | 0.31 ± 0.00a | 0.17 ± 0.01b | 0.19 ± 0.003b | 0.18 ± 0.02b | 0.18 ± 0.01b | ||
408 | 0.30 ± 0.00a | 0.16 ± 0.00b | 0.19 ± 0.01b | 0.18 ± 0.02b | 0.18 ± 0.00b | ||
456 | 0.31 ± 0.03a | 0.16 ± 0.01b | 0.18 ± 0.01b | 0.18 ± 0.00b | 0.18 ± 0.01b | ||
504 | 0.32 ± 0.01a | 0.16 ± 0.01b | 0.17 ± 0.01b | 0.17 ± 0.01b | 0.16 ± 0.00b |