Table 1 Mean score of cellular changes in the pituitary gland of Pre-pubertal Buffalo heifers inoculated with Pasteurella multocida B: 2 and its immunogens (LPS and OMPs)

Group 1 (PBS Control)

0.0 ± 0.0^a

0.0 ± 0.0^a

0.0 ± 0.0^a

0.0 ± 0.0^a

0.0 ± 0.0^a

Group 2 (P.multocida B:2 Oral)

0.42 ± 0.11^b

0.33 ± 0.10^a

0.81 ± 0.12^b

1.52 ± 0.10^b

0.17 ± 0.08^a

Group 3 (P.multocida B:2 Subcutaneous)

2.50 ± 0.18^c

0.33 ± 0.10^a

1.64 ± 0.13^c

2.43 ± 0.15^c

0.42 ± 0.11^b

Group 4 (LPS Oral)

0.58 ± 0.16^b

0.33 ± 0.16^a

0.75 ± 0.15^b

1.45 ± 0.12^b

0.25 ± 0.14^a

Group 5 (LPS Intravenous)

0.67 ± 0.16^b

0.33 ± 0.16^a

0.80 ± 0.11^b

1.05 ± 0.15^b

0.17 ± 0.11^a

Group 6 (OMP Oral)

2.58 ± 0.18^b

0.33 ± 0.14^a

1.35 ± 0.15^c

2.31 ± 0.15^c

0.50 ± 0.17^b

Group 7 (OMP Subcutaneous)

2.75 ± 0.18^c

0.42 ± 0.14^b

1.55 ± 0.10^c

2.44 ± 0.12^c

0.42 ± 0.11^b