TY - JOUR AU - Gerspach, C. AU - Imhasly, S. AU - Klingler, R. AU - Hilbe, M. AU - Hartnack, S. AU - Ruetten, M. PY - 2017 DA - 2017/04/12 TI - Variation in fat content between liver lobes and comparison with histopathological scores in dairy cows with fatty liver JO - BMC Veterinary Research SP - 98 VL - 13 IS - 1 AB - The assessment of a liver biopsy remains the gold standard for diagnosing and staging fatty liver in dairy cows, which is often necessary for diagnostic and research purposes. Accuracy of the diagnosis relays on the quality of the biopsy, the assumed representativeness of a small tissue sample for a disease process throughout the liver and accurate human evaluation of histologic specimens. The objective of the present study was to assess the distribution of triacylglycerol (TAG) infiltration throughout the parenchyma of livers with different degrees of fatty liver in dairy cows. In addition, histopathological scores from the corresponding specimens were compared to a quantitative measurement of TAG, as well as the agreement between two observers. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-017-1004-9 DO - 10.1186/s12917-017-1004-9 ID - Gerspach2017 ER -