FOXO1, PXK, PYCARD and SAMD9L are differentially expressed by fibroblast-like cells in equine synovial membrane compared to joint capsule

Table 3 Microarray Fold change and p-values for the 15 selected candidate genes

Gene symbol	Function	Fold change	p-value ANOVA
ATXN1	Embryonal ECM remodelling	2.48	2.96E-03
COL11A1	Collagen in ECM	11.82	2.93E-04
COL28A1	Collagen in vascular ECM	21.29	1.63E-04
FSTL1	Unknown, embryonal mesenchymal location	4.10	2.59E-03
FOXO1	Transcription factor, function in osteoblast homeostasis	2.33	2,50E-05
GALNT3	Glycosylation, golgi complex	5.65	8.88E-07
GRN	Regulate cell growth	1.99	5.49E-06
ITPR3	Second messenger, possible role in exocrine secretion	3.09	6.64E-04
NF1	Regulate cell growth	3.27	4.35E-04
PXK	A functionel sorting nexin	4.81	1.72E-04
PYCARD	Function in inflammasomes	3.70	8.63E-05
RGL2A	Protein transport in cells	1.58	1.64E-05
SAMD9L	Protein-protein interaction	4.88	5.80E-04
SOS1	Promotes reorganization of actin cytoskeleton	2.90	1.20E-03
TIMP3	Metalloproteinase inhibitor	1.75	9.79E-04

ATXN1 ataxin 1, COL11A1 collagen XI α1, COL28A1 collagen XXVIII α1, FOXO1 forkhead box O1, FSTL1 follistatin-like 1, GALNT3 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNac-T3), GRN granulin, ITPR3 inositol 1,4,5-trisphosphate receptor, type 3, NF1 neurofibromin 1, PXK PX domain containing serine/threonine kinase, PYCARD PYD and CARD domain containing, RGL2 RGL2, ral guanine nucleotide dissociation stimulator-like 2, SAMD9L sterile alpha motif domain containing 9-like, SOS1 son of sevenless homolog 1 (Drosophila), TIMP3 TIMP metallopeptidase inhibitor 3

ISSN: 1746-6148