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Table 3 Concentrations and activity of blood markers of fibrinolysis in complicated (CB) and uncomplicated (UB) canine babesiosis

From: Blood markers of fibrinolysis and endothelial activation in canine babesiosis

Parameter (unit)

Group

N

Median (interquartile range)

P value (UB 0 – CB 0)

P value (UB 0 – UB 6)

P value (CB 0 – CB 6)

P value (UB 6 – CB 6)

PLG (%)

UB, day 0

19

85,0 (81,5–98,0)

0,517

0,019

0,169

0,789

CB, day 0

11

92,5 (83,0–114,0)

UB, day 6

16

101,0 (91,5–125,5)

CB, day 6

11

104,0 (92,0–131,0)

PAI-1 (pg/ml)

UB, day 0

19

255,49 (96,81–519,27)

0,445

0,031

0,594

0,059

CB, day 0

11

148,19 (75,1–323,52)

UB, day 6

17

392,92 (321,44–700,34)

CB, day 6

11

230,09 (117,59–309,24)

TAFI (ng/ml)

UB, day 0

19

481,1 (417,55–538,7)

0,232

0,877

0,037

0,020

CB, day 0

11

440,7 (388,6–481,1)

UB, day 6

16

455,15 (397,3–518,58)

CB, day 6

10

561,6 (475,35–693,45)

suPAR (pg/ml)

UB, day 0

19

4283,75 (3893,05–4729,15)

0,553

0,179

0,333

0,979

CB, day 0

11

4450,9 (3893,05–5006,9)

UB, day 6

16

3725,3 (3305,23–4562,23)

CB, day 6

10

3697,33 (3164,95–5228,75)

  1. PLG plasminogen, PAI-1 plasminogen activator inhibitor-1, TAFI thrombin activatable fibrinolysis inhibitor, suPAR soluble urokinase receptor of plasminogen activator