Table 2 Concentrations of blood markers of endothelial activation in complicated (CB) and uncomplicated (UB) canine babesiosis
From: Blood markers of fibrinolysis and endothelial activation in canine babesiosis
Parameter (unit) | Group | N | Median (interquartile range) | P value (UB 0 – CB 0) | P value (UB 0 – UB 6) | P value (CB 0 – CB 6) | P value (UB 6 – CB 6) |
|---|---|---|---|---|---|---|---|
TM (ng/ml) | UB, day 0 | 19 | 3,77 (2,02–4,58) | 0,933 | <0,001 | 0,003 | 0,471 |
CB, day 0 | 11 | 3,45 (3,13–4,09) | |||||
UB, day 6 | 19 | 1,55 (1,23–1,94) | |||||
CB, day 6 | 11 | 1,39 (1,31–1,55) | |||||
ICAM-1 (ng/ml) | UB, day 0 | 19 | 6,96 (4,95–10,19) | 0,832 | 0,002 | 0,575 | 0,174 |
CB, day 0 | 11 | 6,46 (5,07–11,34) | |||||
UB, day 6 | 18 | 6,24 (3,76–8,09) | |||||
CB, day 6 | 10 | 6,69 (4,94–47,68) | |||||
HMGB-1 (ng/ml) | UB, day 0 | 19 | 44,93 (34,12–109,49) | 0,899 | <0,001 | 0,022 | 0,869 |
CB, day 0 | 11 | 50,84 (29,31–88,1) | |||||
UB, day 6 | 18 | 19,89 (12,73–37,34) | |||||
CB, day 6 | 10 | 15,5 (10,52–73,25) | |||||
VCAM-1 (ng/ml) | UB, day 0 | 19 | 451,25 (429,2–507,4) | 0,004 | 0,199 | 0,093 | 0,247 |
CB, day 0 | 11 | 489,6 (476,3–576,05) | |||||
UB, day 6 | 19 | 494,05 (432,15–547,6) | |||||
CB, day 6 | 10 | 471,88 (417,45–489,6) |