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Table 1 Sensitivity and specificity comparing 1) 123 eqbE LAMP results to the sample type (guttural pouch lavage (GPL) versus not [nasopharyngeal wash, or nasopharyngeal flocked swab]); 2) eqbE LAMP results from 44 GPL samples to abnormal guttural pouch endoscopic findings; 3) eqbE LAMP from 44 GPL samples to empyema found on guttural pouch endoscopy; 4) eqbE LAMP to seeI PCR from 44 GPL samples

From: Comparison of nasopharyngeal and guttural pouch specimens to determine the optimal sampling site to detect Streptococcus equi subsp equi carriers by DNA amplification

   eqbE LAMP Total Sensitivity Specificity PPVb NPVc Correctly Classified ROCd
   Positive Negative        
GPLa Sampling Method Yes 24 7 31 77% 78% 55% 91% 78% 0.83
No 20 72 92
Total 44 79 123
Abnormal Guttural Pouch Endoscopy Yes 20 7 27 74% 70% 80% 63% 72% 0.80
No 5 12 17
Total 25 19 44
Guttural Pouch Empyema Yes 12 1 13 92% 61% 50% 95% 70% 0.85
No 12 19 31
Total 24 20 44
seeI PCR Positive 15 3 18 83% 65% 63% 85% 73% 0.78
Negative 9 17 26
Total 24 20 44
  1. The cutoff probability for sample type is ≥ 0.5
  2. aGuttural Pouch Lavage
  3. bPositive predictive value (based on the detection of S. equi DNA and not on the presence of live organisms)
  4. cNegative predictive value
  5. dReceiver operator curve
  6. All analyses are adjusted for antibiotics usage and the time from last antibiotic treatment by determining if they were significant confounders within the logistic regression via STATA
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