TY - JOUR AU - Zatroch, Katie K. AU - Knight, Cameron G. AU - Reimer, Julie N. AU - Pang, Daniel S. J. PY - 2017 DA - 2017/02/21 TI - Refinement of intraperitoneal injection of sodium pentobarbital for euthanasia in laboratory rats (Rattus norvegicus) JO - BMC Veterinary Research SP - 60 VL - 13 IS - 1 AB - The Canadian Council on Animal Care and American Veterinary Medical Association classify intraperitoneal (IP) pentobarbital as an acceptable euthanasia method in rats. However, national guidelines do not exist for a recommended dose or volume and IP euthanasia has been described as unreliable, with misinjections leading to variable success in ensuring a timely death. The aims of this study were to assess and improve efficacy and consistency of IP euthanasia. SN - 1746-6148 UR - https://doi.org/10.1186/s12917-017-0982-y DO - 10.1186/s12917-017-0982-y ID - Zatroch2017 ER -