Skip to main content

Table 2 Concentrations of cytokines (IL-6, IL-1 and TNF-α), acute phase proteins (CRP, Haptoglobin) and cells in different bodily fluids from control and infected animals

From: Host-pathogen interplay at primary infection sites in pigs challenged with Actinobacillus pleuropneumoniae

 

Control (n = 4)a

Infected (n = 6, c n = 3)

BALF Cytokines:

 IL-6 (pg/ml)

ND

434.2 (ND-2491.5)

 IL-1β (pg/ml)

ND

1166.8 (ND-2808.1)

 TNF-α (pg/ml)

129.5 (ND-410.4)

ND

BALF acute phase proteins:

 CRP (ng/ml)

89.7 (39.5–189.6)

389.7 (192.6–554.4)

 Hp (μg/ml)

6.7 (5.2–9.1)

6.2 (5.1–7.5)

BALF Cells:

 Leukocytes (×109/l)

2.9 (1.8–5.1)

11.4 (7.8–16.9)**

 Lymphocytes (×109/l)

0.1 (0–0.3)

c2.5 (0.8–6.1)

 Alveolar Macrophage (×109/l)

1.7 (1.5–2.3)

c6.2 (4.5–10.6)

 

Infected (pre-infection)b

Infected (8 hpi)

Serum acute phase proteins:

 CRP (μg/ml)

49.7 (18.4–71.5)

202.2 (93.9–309)*

 Hp (mg/ml)

0.7 (0.2–1.1)

0.7 (0.5–1.3)

Saliva acute phase proteins:

 CRP (ng/ml)

3 (1.3–7.4)

27.9 (8.4–37.6)

 Hp (μg/ml)

0.4 (0.2–1)

1.9 (1.3–3.6)*

  1. Results are expressed as median values (interquartile range). aDifferences between control and infected group in the BALF immediately after death. *p ≤ 0.05
  2. **p ≤ 0.01 Wilcoxon rank test. bDifferences within the infected group between the last time point of sampling (8 hpi) and prior to infection. *p ≤ 0.05 Wilcoxon signed ranks test. cLymphocytes and alveolar macrophages were not detectable in the BALF of three animals out of the infection group
  3. ND = not detectable because below detection limit
  4. Significant values are marked in bold
Back to article page

BMC Veterinary Research

ISSN: 1746-6148

Contact us