Table 1 Categories of clinical signs shown by Francisella tularensis ssp. holarctica infected Fischer 344 rats
From: Comparison of virulence of Francisella tularensis ssp. holarctica genotypes B.12 and B.FTNF002-00
Severity of disease | Clinical signs |
|---|---|
Mild | weight loss, accumulation of porphyrin around the eyes (one or both sides), nasal discharge |
Moderate | weight loss, marked porphyrin secretion around the eyes (one or both sides), nasal discharge, ruffled fur, decreased activity, diarrhoea |
Severe | weight loss, marked porphyrin secretion around the eyes (both sides), nasal discharge, ruffled fur, inactivity, diarrhoea, laboured breathing, weakness |