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Table 3 Urinary purine metabolite analytes measured from 24-h urine collections analysed by the capillary electrophoresis method

From: Evaluation of dogs with genetic hyperuricosuria and urate urolithiasis consuming a purine restricted diet: a pilot study

Variable

Baseline (visit 1)

2 month (visit 2)

12 month (visit 4)

P value

Urine volume

685 ± 167

846 ± 167

956 ± 178

0.110

Urine HX conc.

22.9 ± 3.8

18.0 ± 3.8

22.6 ± 4.4

0.581

Urine X conc.

16.4 ± 6.1

13.2 ± 6.1

17.0 ± 6.5

0.766

Urine UA conc.

549 ± 48.2

366 ± 48.2

356 ± 54.6

0.008

Urine ALL conc.

355 ± 83.8

384 ± 83.8

385 ± 92.2

0.713

Urine HX exc.

15.5 ± 2.6

12.4 ± 2.6

13.9 ± 2.9

0.320

Urine X exc.

9.7 ± 2.1

6.71 ± 2.1

9.7 ± 2.3

0.405

Urine UA exc.

361 ± 60.2

306 ± 60.2

271 ± 66.1

0.220

Urine ALL exc.

227 ± 32.3

232 ± 32.3

179 ± 36.5

0.593

  1. Metabolites are reported as both concentrations (conc; in mg/L) and excretions (exc; in mg/24 h), and urine volume is expressed in mL/24 h. Data are presented as the least square means ± standard error. P values result from the contrast method comparing baseline visit to visits 2 and 4 together. UA = uric acid, HX = hypoxanthine, X = xanthine, ALL = allantoin