Table 3 Median, (25th and 75th percentiles) and percentage of median deviation between initial and follow-up samples of biomarkers of tubular damage. In Group 1: dogs that showed proteinuria (UPC > 0.5) before treatment which did not decrease or even increased after treatment; Group 2: dogs that showed proteinuria (UPC > 0.5) before treatment which decreased after treatment
From: Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment
Parameter | Group 1 (n = 6) | Group 2 (n = 12) | Control dogs (n = 10) | ||||
|---|---|---|---|---|---|---|---|
Inital | Follow up | % median deviation | Inital | Follow up | % median deviation | ||
uRBP/Cr (mg/g) | 0.880 (0.049–7.453) | 0.506 (0.173–8.608) | −42.5 | 0.484 (0.227–2.650) | 0.169 (0.037–0.502)* | −65.08 | 0.21 (0–0.99) |
uNAG/Cr (UI/g) | 18.49 (4.35–98.82) | 18.30 (5.64–28.57) | −1.03 | 14.77 (5.31–28.32) | 6.20 (3.84–14.56)* | −58.02 | 7.97 (5.27–11.19) |
uGGT/Cr (UI/g) | 31.3 (20.0–101.8) | 28.4 (9.9–95.2) | −9.26 | 15.38 (11.05–90.36) | 10.78 (7.44–19.63) | −29.91 | 10.99 (8.37–18.87) |