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Table 2 Median, (25th and 75th percentiles) and percentage of median deviation between initial and follow-up samples of biomarkers of glomerular damage. Group 1: dogs that showed proteinuria (UPC > 0.5) before treatment which did not decrease or even increased after treatment; Group 2: dogs that showed proteinuria (UPC > 0.5) before treatment which decreased after treatment

From: Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment

Parameter Group 1 (n = 6) Group 2 (n = 12) Control dogs (n = 10)
Inital Follow up % median deviation Inital Follow up % median deviation
uIgG/Cr (mg/g) 202.7 (31.1–4986.0) 81.5 (3.5–3603.0) -24.8 176.1 (36.6–2996.0) 40.4 (12.9–408.4)** −77.02 0.01 (0.008–0.018)
uCRP/Cr (μg/g) 6.06 (1.87–29.1) 8.38 (1.78–16.1) 38.2 15.40 (4.624–74.67) 3.21 (2.48–5.09)** −79.16 1.03 (0.74–1.89)
uFerr/Cr (μg/g) 27.1 (5.6–45.9) 31.5 (5.2–60.5) 16.2 23.48 (8.95–60.92) 13.71 (5.35–30.57)* −41.61 2.00 (0.58–3.44)
  1. **P<0.01 compared to baseline, *P<0.05 compared to baseline