Table 2 Median, (25th and 75th percentiles) and percentage of median deviation between initial and follow-up samples of biomarkers of glomerular damage. Group 1: dogs that showed proteinuria (UPC > 0.5) before treatment which did not decrease or even increased after treatment; Group 2: dogs that showed proteinuria (UPC > 0.5) before treatment which decreased after treatment
From: Evaluation of various biomarkers for kidney monitoring during canine leishmaniosis treatment
Parameter | Group 1 (n = 6) | Group 2 (n = 12) | Control dogs (n = 10) | ||||
|---|---|---|---|---|---|---|---|
Inital | Follow up | % median deviation | Inital | Follow up | % median deviation | ||
uIgG/Cr (mg/g) | 202.7 (31.1–4986.0) | 81.5 (3.5–3603.0) | -24.8 | 176.1 (36.6–2996.0) | 40.4 (12.9–408.4)** | −77.02 | 0.01 (0.008–0.018) |
uCRP/Cr (μg/g) | 6.06 (1.87–29.1) | 8.38 (1.78–16.1) | 38.2 | 15.40 (4.624–74.67) | 3.21 (2.48–5.09)** | −79.16 | 1.03 (0.74–1.89) |
uFerr/Cr (μg/g) | 27.1 (5.6–45.9) | 31.5 (5.2–60.5) | 16.2 | 23.48 (8.95–60.92) | 13.71 (5.35–30.57)* | −41.61 | 2.00 (0.58–3.44) |